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Sponsored Presentations

Organizations associated with SPS as Exhibiting Companies and/or Sponsors are welcome to host Sponsored Presentations/Functions. All Sponsor Presentations/Functions must be preapproved by SPS Headquarters.

The fee for hosting such an event is $1,250 US, and includes the following: listing on the SPS Annual Meeting website, listing in the SPS final Program, and two premeeting email announcements distributed by SPS Headquarters.

If you have any questions please contact Laura Helm.


Multi-Parametric Analysis of Cardiomyocyte Exictation-Contraction Coupling for Preclinical Cardiac Safety Assessment
12:30 – 13:30
Sponsored by: ACEA Biosciences
Club D

In this session we will describe how the xCELLigence RTCA CardioECR system utilizes impedance and field potential electrodes to measure and assess the adverse effects of pharmaceutical compounds using human iPSC- derived cardiomyocytes. We will show how the simultaneous readout of contractility and electrophysiology allows for detection of specific and measurable effects of certain drug toxicities which can be missed by other readouts. Furthermore, we will demonstrate how the non-invasive readouts can measure both acute and long term toxicities associated with pharmaceutical compounds such as kinase inhibitors.

CiPA+: More Buckets
12:30 – 13:30
Sponsored by: ChanTest, a Charles River Company
Club C

CIPA is a new paradigm for nonclinical assessment of cardiac risk during acute exposure.  It uses MoA based in vitro assays and in silico reconstructions of human ventricular action potentials. During this presentation, simulations will be compared with experimental iPSC-derived cardiomyocyte action potentials.  The extension of  CiPA to include the more common clinical situation namely subacute and chronic exposure will also be considered. 

Are you Ready for CiPA? Sophion is.
12:30 – 13:30
Sponsored by: Sophion – Part of Biolin Scientific
Club E

The CiPA paradigm is currently being described from the CiPA ion channel work group, where Sophion is part of the panel.
We will update you on the progress and the new voltage protocols comings into play. Sophion supports you all the way from assay set-up to analysis.

DSI’s 8th Annual Scientific Data Blast
18:00 – 19:00
Sponsored by: Data Sciences International

Do you like learning about the latest safety pharmacology developments?  Then join us for this educational and entertaining event to network and enjoy a cocktail while your colleagues present their latest scientific discoveries in an abbreviated format.  Refreshments will be served.



Emerging Drug Candidates for Pulmonary Arterial Hypertension: The Ups and Downs of Multiple Animal Models
12:30 – 13:30
Sponsored by: CorDynamics
Club C

Enjoy lunch while discussing an R&D hot topic—pulmonary arterial hypertension (PAH). Dr. Franz Hock and Dr. Michael Gralinski will present the differences (and benefits) of monocrotaline, hypoxio with/without VEGF inhibition, and immunodeficiency as preclinical initiators of PAH. Learn how your compounds may prevent/reverse this condition on the path to clinic.

Warning: This is a high-speed scientific presentation that includes sudden and dramatic discussions of data and pharmacology. CorDynamics assumes no responsibility for disappointment incurred from expecting a tedious sales pitch.

Unlock the information in your data using DSI’s new Data Insights™ Software
12:30 – 13:30
Sponsored by: Data Sciences International
Club E

Learn firsthand how DSI’s Data Insights simplifies arrhythmia detection and accelerates results.  Presenters will offer perspectives on:
• Arrhythmia detection in Safety Pharmacology and Toxicology studies
• Incorporating Data Insights into analysis workflows
• Using Data Insights to improve data throughput
Lunch will be provided.

Complementary automated patch clamp, extracellular field potential and impedance recordings: drug and safety screening tool box for the future not only for iPS cardiomyocytes
12:30 – 13:30
Sponsored by: Nanion Technologies
Club D

Nanion customers will showcase their safety screening efforts according to CiPA standards, using automated patch clamp systems and systems supporting EFP- and impedance-  read outs from beating networks of stem cell-derived cardiomyocytes. The session will have a strong focus on ways to improving reliability and efficiency in cardiotoxicity screening.

Advancements in Human iPSC-derived cardiomyocytes and MEA technology make for robust, higher throughput proarrhythmia assessments with Less Cell Handling and Shorter Assay Times
18:00 – 19:00
Sponsored by: Cellular Dynamics & Axion BioSystems
Club E

Improvements in human iPSC-cardiomyocytes and analytical platforms continues to enable early-stage predictive proarrythmia assays.
This workshop will present MEA results from multiple sites conducting the pilot CiPA study, provide an update on new iPSC-cardiomyocyte products, and present new higher throughput data collection and analysis techniques.
Audience participation is strongly encouraged.

Novel Aspects of in vitro cardiotoxicology testing with the Clyde Biosciences CellOPTIQ
18:00 – 19:00
Sponsored by: Clyde Biosciences
Club D

This session will provide four 15 minute talks on various aspects of cardiotoxicology including: (i) the HESA CiPA study (II) a collaborative study with the FDA relating electrical signals from iPS cardiomyocytes to human ECG parameters (iii) cardiac excitability studied with optogenetic probes and (iv) excitation-contraction in adult ventricle cells and iPS-cardiomyocytes.

How Drug Precedents can inform Critical Drug Development Decisions
18:00 – 19:00
Sponsored by: Elsevier R& D Solutions
Club C

Plan to attend talks by leading scientists from major pharmaceutical companies on the innovative ways they leverage regulatory evidence to address challenges in preclinical and clinical development. This is an excellent opportunity to meet the speakers and your fellow researchers afterward over snacks and cocktails.


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